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KMID : 1129720030200010065
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Korean Journal of Acupuncture
2003 Volume.20 No. 1 p.65 ~ p.70
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The Potential of Cnidium officinale Makino as the Component of Gamgungtang to Induce the Phase II Enzyme in vivo
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Han Sang-Hoon
Shon Yun-Hee
Kim Hyuck
Lee Hee-soon
Park In-Kyung
Nam Kyung-Soo
Kim Cheorl-Ho
Lim Jong-Kook
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Abstract
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The activity of phase II enzyme in the liver of mice was examined following the application of Cnidium officinale Makino aqua-acupuncture solution (COMAS). The application of COMAS CV12 to mice for 7 days increased quinone reductase(QR) activity. The glutathione S-transferase(GST) activity was also increased with COMAS. A greater increase was observed in the glutathione(GSH) levels than in the QR and GST activities.
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KEYWORD
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Cnidium officinale Makino, Quinone reductase(QR), Glutathione S-transferase(GST), Glutathione (GSH)
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